The Colorado office of the Bureau of Land Management (BLM), has been charged with developing a climate adaptation strategy for BLM lands within the state. The Colorado Natural Heritage Program conducted climate change vulnerability assessments of plant and animal species, and terrestrial and freshwater ecosystems ("targets") within a time frame of mid-21st century. Our assessments 1) evaluate the potential impact of future climate conditions on both species and ecosystems by identifying the degree of change expected between current and future climate conditions within the Colorado range of the target, and 2) address the potential impact of non-climate factors that can affect the resilience of the target to climate change, or which are likely to have a greater impact due to climate change.