This report is organized as follows: Section One describes the mandate to report per Senate Bill 13-283, data sources and the data collection methods used, the history of marijuana laws in Colorado, and the federal response. Section Two focuses on the public safety impacts of marijuana legalization while Section 3 presents information concerning public health. Section 4 presents impacts on youth, Section 5 provides additional information, and Section 6 summarizes the challenges involved in measuring the impact of legalization.